Some publications

Agrawal S, Fox J, Thyagarajan B, Fox JH. Brain mitochondrial iron accumulates in Huntington’s disease, mediates mitochondrial dysfunction, and can be removed pharmacologically. Free Radic Biol Med. 2018 May 20; 120:317-329. doi: 10.1016/j.freeradbiomed.2018.04.002.

Agrawal S, Berggren KL, Marks E, Fox JH.  Impact of high iron intake on cognition and neurodegeneration in humans and in animal models: a systematic review.  Nutr Rev.  2017. doi: 10.1093/nutrit/nux015.

Donley DW, Olson AR, Raisbeck MF, Fox JH, Gigley JP.  Huntington’s disease mice infected with Toxoplasma gondii demonstrate early kynurenine pathway activation, altered CD8+ T-cell responses, and premature mortality.  2016.  PLoS ONE 11(9): e0162404. doi:10.1371/journal.pone.0162404

Berggren KL, Chen J, Fox J, Miller J, Dodds L, Dugas B, Vargas L, Lothian A, McAllum E, Volitakis I, Roberts B, Bush AI, Fox JH.  Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington’s disease.  Redox Biol. 2015;4:363-74. doi: 10.1016/j.redox.2015.02.002.

Dodds L, Chen J, Berggren K, Fox J. Characterization of Striatal Neuronal Loss and Atrophy in the R6/2 Mouse Model of Huntington’s Disease.  PLOS Currents Huntington Disease. 2014. doi: 10.1371/currents.hd.48727b68b39b82d5fe350f753984bcf9.

Fox JH, Connor T, Stiles M, Kama J, Lu Z, Dorsey K, Liebermann G, Sapp E, Cherny RA, Banks M, Volitakis I, Difiglia M, Berezovska O, Bush AI, Hersch SM.  Cysteine Oxidation within N-terminal Mutant Huntingtin Promotes Oligomerization and Delays Clearance of Soluble Protein.  J Biol Chem. 2011; 286(20): 18320-30.

View Google Scholar >